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    This Project is part of the following research programme/s:

    Fertility and Family

    Overview

    This research project explores sexual behaviour and relationship dynamics in the era of antiretroviral therapy (ART) rollout in South Africa. Using both primary and secondary data the project a series of studies are undertaken;

    A prospective clinic study of HIV-infected people to compare rates of partnership change and patterns of sexual behaviour between two groups; those on ART vs those not yet eligible for ART.
    Analyses of longitudinal data collected as part of the Africa Centre HIV surveillance to examine the impact of ART on sexual behaviours.
    A cross-sectional survey investigating living arrangements, partnership patterns and sexual behaviour of migrants.
    For more information see the Africa Centre website.

    Publications & Activities

    Isisekelo Sempilo study protocol for the effectiveness of HIV prevention embedded in sexual health with or without peer navigator support (Thetha Nami)...
    BMC Public Health (2022). 22 (454)
    Authors: Chidumwa G, Chimbindi N, Herbst C, Okesola N, Dreyer J, Zuma T, Smit T, Molina J, Khoza T, McGrath N, Seeley J, Pillay D, Tanser F, Harling G, Sherr L, Copas A, Baisley K, Shahmanesh M,

    Protocol: Mapping social networks, social influence and sexual health among youth in rural KwaZulu-Natal, the Sixhumene cohort study
    Wellcome Open Res (2022). 7 (164)
    Authors: Nxumalo V, Nxumalo S, Smit T, Khoza T, Mdaba F, Khumalo T, Cislaghi B, McGrath N, Seeley J, Shahmanesh M, Harling G,

    The association of exposure to DREAMS on sexually acquiring or transmitting HIV amongst adolescent girls and young women living in rural South Africa: a cohort study
    Aids (2022). 36 (1)
    Authors: Mthiyane N, Baisley K, Chimbindi N, Zuma T, Okesola N, Dreyer J, Herbst C, Smit T, Danaviah S, McGrath N, Harling G, Sherr L, Seeley J, Floyd S, Birdthistle I, Shahmanesh M,

    Process evaluation of peer-to-peer delivery of HIV self-testing and sexual health information to support HIV prevention among youth in rural KwaZulu-Natal, South Africa: qualitative analysis
    BMJ Open (2022). 12 (2)
    Authors: Adeagbo O, Seeley J, Gumede D, Xulu S, Dlamini N, Luthuli M, Dreyer J, Herbst C, Cowan F, Chimbindi N, Hatzold K, Okesola N, Johnson C, Harling G, Subedar H, Sherr L, McGrath N, Corbett E, Shahmanesh M,

    Effect of Peer-distributed HIV self-test kits on demand for biomedical HIV prevention in rural KwaZulu-Natal, South Africa: a three-armed cluster-randomised trial comparing social-networks versus direct delivery
    BMJ Global Health (2021). 6 (4)
    Authors: Shahmanesh M, Mthiyane N, Herbst C, Neuman M, Adeagbo O, Mee P, Dreyer J, Chimbindi N, Smit T, Okesola N, Zuma T, Harling G, McGrath N, Sherr L, Seeley J, Subedar H, Johnson C, Hatzold K, Terris-Prestholt F, Cowan F, Corbett E,

    Thetha Nami : participatory development of a peer-navigator intervention to deliver biosocial HIV prevention for adolescents and youth in rural South Africa
    BMC Public Health (2021). 21 (1)
    Authors: Shahmanesh M, Okesola N, Chimbindi N, Zuma T, Mthiyane N, Adeagbo O, Dreyer J, Herbst C, Mdluli S, McGrath N, Harling G, Sherr L, Seeley J,

    Acceptability of a tablet-based application to support early HIV testing among men in rural KwaZulu-Natal, South Africa: a mixed method study
    AIDS Care : Pyschological and socio-medical aspects of AIDS/HIV (2020). 33 (4) 494-501
    Authors: Adeagbo O, Kim H, Tanser F, Xulu S, Dlamini N, Gumede V, Mathenjwa T, Bärnighausen T, McGrath N, Blandford A, Seeley J, Shahmanesh M,

    Young people's experiences of sexual and reproductive health interventions in rural KwaZulu-Natal, South Africa
    International Journal of Adolescence and Youth (2020). 25 (1) 1058-1075
    Authors: Zuma T, Seeley J, Mdluli S, Chimbindi N, McGrath N, Floyd S, Birdthistle I, Harling G, Sherr L, Shahmanesh M,

    No effect of test and treat on sexual behaviours at population level in rural South Africa
    Aids (2019). 33 (4) 709-722
    Authors: Rolland M, McGrath N, Tiendrebeogo T, Larmarange J, Pillay D, Dabis F, Orne-Gliemann J,

    Retention in Care Trajectories of HIV-Positive Individuals Participating in a Universal Test-and-Treat Program in Rural South Africa (ANRS 12249 TasP Trial)
    Journal of Acquired Immune Deficiency Syndromes (2019). 80 (4) 375-385
    Authors: Gosset A, Protopopescu C, Larmarange J, Orne-Gliemann J, McGrath N, Pillay D, Dabis F, Iwuji C, Boyer S,

    High HIV incidence and low uptake of HIV prevention services: The context of risk for young male adults prior to DREAMS in rural KwaZulu-Natal, South Africa
    Plos One (2018). 13 (12)
    Authors: Baisley K, Chimbindi N, Mthiyane N, Floyd S, McGrath N, Pillay D, Seeley J, Zuma T, Dreyer J, Gareta D, Smit T, Mutevedzi T, Fenty J, Herbst K, Birdthistle I, Shahmanesh M,

    The impact of population dynamics on the population HIV carecascade: results from the ANRS 12249 Treatment as Preventiontrial in rural KwaZulu-Natal (South Africa)
    Journal of the International Aids Society (2018). 21 (6)
    Authors: Larmarange J, Hassimiou-Diallo M, McGrath N, Iwuji C, Plazy M, Thiebaut R, Tanser F, Bärnighausen T, Dabis F, Orne-Gliemann J,

    Alcohol use and relationship quality among South African couples
    Journal of Substance Use & Misuse (2018).
    Authors: Woolf-King S, Conroy A, Johnson M, Hosegood V, Van-Rooyen H, Darbes L, McGrath N,

    Persistently high incidence of HIV and poor service uptake in adolescent girls and young women in rural KwaZulu-Natal, South Africa prior to DREAMS
    Plos One (2018).
    Authors: Chimbindi N, Mthiyane N, Birdthistle I, Floyd S, McGrath N, Pillay D, Seeley J, Zuma T, Dreyer J, Gareta D, Mutevedzi T, Fenty J, Herbst K, Smit T, Baisley K, Shahmanesh M,

    Prevalence of sexually transmitted infections among young people in South Africa: A nested survey in a health and demographic surveillance site
    PLoS Medicine (2017).
    Authors: Francis S, Francis S, Mthiyane N, Baisley K, Mchunu L, Ferguson J, Smit T, Crucitti T, Gareta D, Dlamini S, Mutevedzi T, Seeley J, Pillay D, Shahmanesh M, McGrath N,

    Perceptions of the immediate social context of HIV risk behaviour
    AIDS Impact 13th International Conference (2017). (Cape Town)
    Authors: Ngwenya N, Gumede D, McGrath N, Shahmanesh M, Seeley J,

    Reproductive tract infections among young people at risk for HIV acquisition: Results from a population-based survey among young people in rural KwaZulu-Natal, South Africa
    AIDS Impact 13th International Conference (2017). (Cape Town)
    Authors: Francis S, Mchunu S, Mthiyane T, Baisley K, Ferguson J, Smit T, Dlamini S, Mutevedzi T, Seeley J, Shahmanesh M, McGrath N,

    HIV testing models and their implications for patient engagement with HIV care and treatment on the eve of "test and treat" findings from the Bottlenecks study
    AIDS Conference 2016 (2016). (Durban, South Africa)
    Authors: Wringe A, Moshabela M, Nyamukapa C, Bukenya D, Odongo O, Renju J, Seeley J, Ddaaki W, Church K, Hosegood V, Bonnington O,

    Adult life expectancy trends in the era of antiretroviral therapy in sub-Saharan Africa.
    20th International AIDS Conference (2014). (Melbourne)
    Authors: Reniers G, Hosegood V,

    Scale and distribution of excess deaths among HIV positive adults by diagnosis, care and treatment history in African population based cohorts 2007-2011.
    20th International AIDS Conference (2014). (Melbourne)
    Authors: Slaymaker E, Hosegood V,

    A comparative analysis of national HIV policies in six African countries with generalised epidemics: Influences on access to testing, access to treatment and retention in care.
    20th International AIDS Conference (2014). (Melbourne)
    Authors: Zaba B, Hosegood V,

    Population-level trends in the uptake of HIV/AIDS services and the survival of HIV positives: evidence from that of demographic surveillance sites in eastern and southern Africa.
    20th International AIDS Conference (2014). (Melbourne)
    Authors: Reniers G, Hosegood V,

    Summarizing current trends in HIV incidence: lifetime infection risk in five community-based longitudinal studies in sub-Saharan Africa in the era of ART roll-out.
    20th International AIDS Conference (2014). (Melbourne)
    Authors: Zaba B, Hosegood V,


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    Authors: Chidumwa G, Chimbindi N, Herbst C, Okeselo N, Dreyer J, Zuma T, Smit T, Molina J, Khoza T, McGrath N, Seeley J, Pillay D, Tanser F, Harling G, Sherr L, Copas A, Baisley K, Shahmanesh M,