Projects
Partnerships and sexual behaviour in the era of ART in South Africa
Project contributors: McGrath N,
This Project is part of the following research programme/s:
Overview
This research project explores sexual behaviour and relationship dynamics in the era of antiretroviral therapy (ART) rollout in South Africa. Using both primary and secondary data the project a series of studies are undertaken;
A prospective clinic study of HIV-infected people to compare rates of partnership change and patterns of sexual behaviour between two groups; those on ART vs those not yet eligible for ART.
Analyses of longitudinal data collected as part of the Africa Centre HIV surveillance to examine the impact of ART on sexual behaviours.
A cross-sectional survey investigating living arrangements, partnership patterns and sexual behaviour of migrants.
For more information see the Africa Centre website.
Publications & Activities
Isisekelo Sempilo study protocol for the effectiveness of HIV prevention embedded in sexual health with or without peer navigator support (Thetha Nami)...
BMC Public Health (2022). 22 (454)
Authors: Chidumwa G, Chimbindi N, Herbst C, Okesola N, Dreyer J, Zuma T, Smit T, Molina J, Khoza T, McGrath N, Seeley J, Pillay D, Tanser F, Harling G, Sherr L, Copas A, Baisley K, Shahmanesh M,
Protocol: evaluation of an optimised couples-focused intervention to increase testing for HIV in rural KwaZulu-Natal, South Africa, the Igugu Lethu ('Our treasure') cohort study
BMC Public Health (2022). 22
Authors: McGrath N, Ngcobo N, Feng Z, Joseph P, Dladla P, Ngubane T, Hosegood V, Morton K, Van-Rooyen H, Van-Heerden A,
Protocol: Mapping social networks, social influence and sexual health among youth in rural KwaZulu-Natal, the Sixhumene cohort study
Wellcome Open Res (2022). 7 (164)
Authors: Nxumalo V, Nxumalo S, Smit T, Khoza T, Mdaba F, Khumalo T, Cislaghi B, McGrath N, Seeley J, Shahmanesh M, Harling G,
The association of exposure to DREAMS on sexually acquiring or transmitting HIV amongst adolescent girls and young women living in rural South Africa: a cohort study
Aids (2022). 36 (1) 39-49
Authors: Mthiyane N, Baisley K, Chimbindi N, Zuma T, Okesola N, Dreyer J, Herbst C, Smit T, Danaviah S, McGrath N, Harling G, Sherr L, Seeley J, Floyd S, Birdthistle I, Shahmanesh M,
Process evaluation of peer-to-peer delivery of HIV self-testing and sexual health information to support HIV prevention among youth in rural KwaZulu-Natal, South Africa: qualitative analysis
BMJ Open (2022). 12 (2)
Authors: Adeagbo O, Seeley J, Gumede D, Xulu S, Dlamini N, Luthuli M, Dreyer J, Herbst C, Cowan F, Chimbindi N, Hatzold K, Okesola N, Johnson C, Harling G, Subedar H, Sherr L, McGrath N, Corbett E, Shahmanesh M,
Optimising a couples-focused intervention to increase couples' HIV testing and counselling using the person-based approach: a qualitative study in Kwa-Zulu Natal, South Africa
BMJ Open (2021). 11 (12)
Authors: Morton K, Mhlakwaphalwa T, Msimango L, Van-Heerden A, Ngubane T, Joseph P, Ngcobo N, Feng Z, Hosegood V, Van-Rooyen H, McGrath N,
Effect of Peer-distributed HIV self-test kits on demand for biomedical HIV prevention in rural KwaZulu-Natal, South Africa: a three-armed cluster-randomised trial comparing social-networks versus direct delivery
BMJ Global Health (2021). 6 (4)
Authors: Shahmanesh M, Mthiyane N, Herbst C, Neuman M, Adeagbo O, Mee P, Dreyer J, Chimbindi N, Smit T, Okesola N, Zuma T, Harling G, McGrath N, Sherr L, Seeley J, Subedar H, Johnson C, Hatzold K, Terris-Prestholt F, Cowan F, Corbett E,
Thetha Nami : participatory development of a peer-navigator intervention to deliver biosocial HIV prevention for adolescents and youth in rural South Africa
BMC Public Health (2021). 21 (1)
Authors: Shahmanesh M, Okesola N, Chimbindi N, Zuma T, Mthiyane N, Adeagbo O, Dreyer J, Herbst C, Mdluli S, McGrath N, Harling G, Sherr L, Seeley J,
Social influence and uptake of couples HIV testing and counselling in KwaZulu‑natal, South Africa.
Aids and Behavior (2021). 26 764-774
Authors: Johnson M, Darbes L, Hosegood V, Johnson M, Fritz K, Ngubane T, Van-Rooyen H, McGrath N,
Acceptability of a tablet-based application to support early HIV testing among men in rural KwaZulu-Natal, South Africa: a mixed method study
AIDS Care : Pyschological and socio-medical aspects of AIDS/HIV (2020). 33 (4) 494-501
Authors: Adeagbo O, Kim H, Tanser F, Xulu S, Dlamini N, Gumede V, Mathenjwa T, Bärnighausen T, McGrath N, Blandford A, Seeley J, Shahmanesh M,
Young people's experiences of sexual and reproductive health interventions in rural KwaZulu-Natal, South Africa
International Journal of Adolescence and Youth (2020). 25 (1) 1058-1075
Authors: Zuma T, Seeley J, Mdluli S, Chimbindi N, McGrath N, Floyd S, Birdthistle I, Harling G, Sherr L, Shahmanesh M,
Early ART initiation improves HIV status disclosure and social support in people living with HIV, linked to care within a universal test and treat program in rural South Africa (ANRS 12249 TasP Trial)
AIDS and Behavior (2020). 25 1306-1322
Authors: Fiorentino M, Nishimwe M, Protopopescu C, Iwuji C, Okesola N, Spire B, Orne-Gliemann J, McGrath N, Pillay D, Dabis F, Larmarange J, Boyer S,
No effect of test and treat on sexual behaviours at population level in rural South Africa
Aids (2019). 33 (4) 709-722
Authors: Rolland M, McGrath N, Tiendrebeogo T, Larmarange J, Pillay D, Dabis F, Orne-Gliemann J,
Female adherence self-efficacy before and after couple HIV testing and counseling within Malawi's Option B+ program
Aids Care (2019). 32 (2) 170-174
Authors: Wesevich A, Hosseinipour M, Golin C, McGrath N, Tsidya M, Chimndozi L, Bhushan N, Hoffman I,
The association between a detectable HIV viral load and non-communicable diseases comorbidity in HIV positive adults on antiretroviral therapy in Western Cape, South Africa
BMC Infectious Diseases (2019). 19 (348)
Authors: George S, McGrath N, Oni T,
Retention in Care Trajectories of HIV-Positive Individuals Participating in a Universal Test-and-Treat Program in Rural South Africa (ANRS 12249 TasP Trial)
Journal of Acquired Immune Deficiency Syndromes (2019). 80 (4) 375-385
Authors: Gosset A, Protopopescu C, Larmarange J, Orne-Gliemann J, McGrath N, Pillay D, Dabis F, Iwuji C, Boyer S,
High HIV incidence and low uptake of HIV prevention services: The context of risk for young male adults prior to DREAMS in rural KwaZulu-Natal, South Africa
Plos One (2018). 13 (12)
Authors: Baisley K, Chimbindi N, Mthiyane N, Floyd S, McGrath N, Pillay D, Seeley J, Zuma T, Dreyer J, Gareta D, Smit T, Mutevedzi T, Fenty J, Herbst K, Birdthistle I, Shahmanesh M,
Community perceptions of the socioeconomic structural context influencing HIV and TB risk, prevention and treatment in a high prevalence area in the era of ART
African Journal of AIDS Research (2018). 17 (1) 72-81
Authors: Ngwenya N, Gumede D, Shahmanesh M, McGrath N, Grant A, Seeley J,
The impact of population dynamics on the population HIV carecascade: results from the ANRS 12249 Treatment as Preventiontrial in rural KwaZulu-Natal (South Africa)
Journal of the International Aids Society (2018). 21 (6)
Authors: Larmarange J, Hassimiou-Diallo M, McGrath N, Iwuji C, Plazy M, Thiebaut R, Tanser F, Bärnighausen T, Dabis F, Orne-Gliemann J,
Alcohol use and relationship quality among South African couples
Journal of Substance Use & Misuse (2018).
Authors: Woolf-King S, Conroy A, Johnson M, Hosegood V, Van-Rooyen H, Darbes L, McGrath N,
Persistently high incidence of HIV and poor service uptake in adolescent girls and young women in rural KwaZulu-Natal, South Africa prior to DREAMS
Plos One (2018).
Authors: Chimbindi N, Mthiyane N, Birdthistle I, Floyd S, McGrath N, Pillay D, Seeley J, Zuma T, Dreyer J, Gareta D, Mutevedzi T, Fenty J, Herbst K, Smit T, Baisley K, Shahmanesh M,
Prevalence of sexually transmitted infections among young people in South Africa: A nested survey in a health and demographic surveillance site
PLoS Medicine (2017).
Authors: Francis S, Francis S, Mthiyane N, Baisley K, Mchunu L, Ferguson J, Smit T, Crucitti T, Gareta D, Dlamini S, Mutevedzi T, Seeley J, Pillay D, Shahmanesh M, McGrath N,
It doesn't help to run away - HIV counselling and testing experiences of people living with HIV in rural KwaZulu-Natal, South Africa: A formative qualitative study
AIDS Impact 13th International Conference (2017). (Cape Town)
Authors: Gumede D, Ngwenya N, McGrath N, Shahmanesh M, Seeley J,
Perceptions of the immediate social context of HIV risk behaviour
AIDS Impact 13th International Conference (2017). (Cape Town)
Authors: Ngwenya N, Gumede D, McGrath N, Shahmanesh M, Seeley J,
Reproductive tract infections among young people at risk for HIV acquisition: Results from a population-based survey among young people in rural KwaZulu-Natal, South Africa
AIDS Impact 13th International Conference (2017). (Cape Town)
Authors: Francis S, Mchunu S, Mthiyane T, Baisley K, Ferguson J, Smit T, Dlamini S, Mutevedzi T, Seeley J, Shahmanesh M, McGrath N,
Side effects among persons using antiretroviral treatment are associated with an increased risk of concurrent usage of multiple sources of healthcare: A prospective observational cohort study
AIDS Impact 13th International Conference (2017). (Cape Town)
Authors: Moshabela M, Vermaak K,
Do fertility intentions predict future fertility among adults in an HIV care programme? A cohort study in KwaZulu-Natal, South Africa
AIDS Impact 13th International Conference (2017). (Cape Town)
Authors: McGrath N, Grapsa E,
The impact of early ART initiation on HIV disclosure and social support among people living with HIV and followed within a universal test and treat programme in rural South Africa (ANRS 12249 TasP trial)
AIDS Impact 13th International Conference (2017). (Cape Town)
Authors: Nishimwe M, Protopopescu C, Iwuji C, Okesola N, Spire B, Orne-Gliemann J, McGrath N, Pillay D, Dabis F, Larmarange J, Boyer S,
Does ART change partnership dynamics and HIV risk behaviours among PLWH? A cohort study in KwaZulu-Natal, South Africa
AIDS (2017). 31 (10) 1451-1460
Authors: McGrath N, Grapsa E,
Baseline for a DREAM: recent trends in sexual behaviour and HIV knowledge among adolescents and young adults in rural KwaZulu-Natal, South Africa
AIDS Conference 2016 (2016). (Durban, South Africa)
Authors: McGrath N, Eaton J, Hosegood V, Birdthistle I, Doyle A, Ferguson J,
Exploring participants' understanding and concerns relating to questions about anal sex in a rural KwaZulu-Natal setting: a cognitive interviewing approach
AIDS Conference 2016 (2016). (Durban, South Africa)
Authors: Gumede D, Mutevedzi T, McGrath N, Barnighausen T, Pillay D, Seeley J, Harling G,
HIV testing models and their implications for patient engagement with HIV care and treatment on the eve of "test and treat" findings from the Bottlenecks study
AIDS Conference 2016 (2016). (Durban, South Africa)
Authors: Wringe A, Moshabela M, Nyamukapa C, Bukenya D, Odongo O, Renju J, Seeley J, Ddaaki W, Church K, Hosegood V, Bonnington O,
Positive impact of a randomized controlled trial of the Uthando Lwethu ("Our Love") intervention on rates of couples HIV testing in rural South Africa
AIDS Conference 2016 (2016). (Durban, South Africa)
Authors: Darbes L, McGrath N, Johnson M, Hosegood V, Fritz K, Ngubane T, Van-Rooyen H,
Time to eligibility for antiretroviral therapy in adults with CD4 cell count > 500 cells/μL in rural KwaZulu-Natal, South Africa
HIV Medicine (2015). 16 (8) 512-518
Authors: McGrath N, Lessels R, Newell M,
Adult life expectancy trends in the era of antiretroviral therapy in sub-Saharan Africa.
20th International AIDS Conference (2014). (Melbourne)
Authors: Reniers G, Hosegood V,
Scale and distribution of excess deaths among HIV positive adults by diagnosis, care and treatment history in African population based cohorts 2007-2011.
20th International AIDS Conference (2014). (Melbourne)
Authors: Slaymaker E, Hosegood V,
A comparative analysis of national HIV policies in six African countries with generalised epidemics: Influences on access to testing, access to treatment and retention in care.
20th International AIDS Conference (2014). (Melbourne)
Authors: Zaba B, Hosegood V,
Population-level trends in the uptake of HIV/AIDS services and the survival of HIV positives: evidence from that of demographic surveillance sites in eastern and southern Africa.
20th International AIDS Conference (2014). (Melbourne)
Authors: Reniers G, Hosegood V,
Summarizing current trends in HIV incidence: lifetime infection risk in five community-based longitudinal studies in sub-Saharan Africa in the era of ART roll-out.
20th International AIDS Conference (2014). (Melbourne)
Authors: Zaba B, Hosegood V,
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Authors: Chidumwa G, Chimbindi N, Herbst C, Okeselo N, Dreyer J, Zuma T, Smit T, Molina J, Khoza T, McGrath N, Seeley J, Pillay D, Tanser F, Harling G, Sherr L, Copas A, Baisley K, Shahmanesh M,
Media
Southampton researcher receives one of two new NIHR Global Health Research Professorships University of Southampton website. 2018