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    This Project is linked to the following Strand/s:

    Fertility and Family

    Overview

    This research project explores sexual behaviour and relationship dynamics in the era of antiretroviral therapy (ART) rollout in South Africa. Using both primary and secondary data the project a series of studies are undertaken;

    A prospective clinic study of HIV-infected people to compare rates of partnership change and patterns of sexual behaviour between two groups; those on ART vs those not yet eligible for ART.
    Analyses of longitudinal data collected as part of the Africa Centre HIV surveillance to examine the impact of ART on sexual behaviours.
    A cross-sectional survey investigating living arrangements, partnership patterns and sexual behaviour of migrants.
    For more information see the Africa Centre website.

    Publications & Activities

    Universal test and treat and the HIV epidemic in rural South Africa: A phase 4, open-label, community cluster randomised trial
    The Lancet HIV (2018). 5 (3) 116-125
    Authors: Iwuji C, Orne-Gliemann J, Larmarange J, Balestre E, Thiebaut R, Tanser F, Okesola N, Makowa T, Dreyer J, Herbst K, McGrath N, Barnighausen T, Boyer S, De-Oliveira T, Rekacewicz C, Bazin B, Newell M, Pillay D, Dabis F,

    Alcohol use and relationship quality among South African couples
    Journal of Substance Use & Misuse (2018).
    Authors: Woolf-King S, Conroy A, Johnson M, Hosegood V, Van-Rooyen H, Darbes L, McGrath N,

    The impact of population dynamics on the population HIV carecascade: results from the ANRS 12249 Treatment as Preventiontrial in rural KwaZulu-Natal (South Africa)
    Journal of the International Aids Society (2018). 21 (6)
    Authors: Larmarange J, Hassimiou-Diallo M, McGrath N, Iwuji C, Plazy M, Thiebaut R, Tanser F, Bärnighausen T, Dabis F, Orne-Gliemann J,

    Impact of Point-of-care Xpert MTB/RIF on Tuberculosis Treatment Initiation: A Cluster Randomised Trial
    American Journal of Respiratory and Critical Care Medicine (2017). 196 (7)
    Authors: Lessels R, Cooke G, McGrath N, Nicol M, Newell M, Godfrey-Fausett P,

    Reproductive tract infections among young people at risk for HIV acquisition: Results from a population-based survey among young people in rural KwaZulu-Natal, South Africa
    AIDS Impact 13th International Conference (2017). (Cape Town)
    Authors: Francis S, Mchunu S, Mthiyane T, Baisley K, Ferguson J, Smit T, Dlamini S, Mutevedzi T, Seeley J, Shahmanesh M, McGrath N,

    Prevalence of sexually transmitted infections among young people in South Africa: A nested survey in a health and demographic surveillance site
    PLoS Medicine (2017).
    Authors: Francis S, Francis S, Mthiyane N, Baisley K, Mchunu L, Ferguson J, Smit T, Crucitti T, Gareta D, Dlamini S, Mutevedzi T, Seeley J, Pillay D, Shahmanesh M, McGrath N,

    Perceptions of the immediate social context of HIV risk behaviour
    AIDS Impact 13th International Conference (2017). (Cape Town)
    Authors: Ngwenya N, Gumede D, McGrath N, Shahmanesh M, Seeley J,

    HIV testing models and their implications for patient engagement with HIV care and treatment on the eve of "test and treat" findings from the Bottlenecks study
    AIDS Conference 2016 (2016). (Durban, South Africa)
    Authors: Wringe A, Moshabela M, Nyamukapa C, Bukenya D, Odongo O, Renju J, Seeley J, Ddaaki W, Church K, Hosegood V, Bonnington O,

    Adult life expectancy trends in the era of antiretroviral therapy in sub-Saharan Africa.
    20th International AIDS Conference (2014). (Melbourne)
    Authors: Reniers G, Hosegood V,

    Summarizing current trends in HIV incidence: lifetime infection risk in five community-based longitudinal studies in sub-Saharan Africa in the era of ART roll-out.
    20th International AIDS Conference (2014). (Melbourne)
    Authors: Zaba B, Hosegood V,

    Population-level trends in the uptake of HIV/AIDS services and the survival of HIV positives: evidence from that of demographic surveillance sites in eastern and southern Africa.
    20th International AIDS Conference (2014). (Melbourne)
    Authors: Reniers G, Hosegood V,

    Scale and distribution of excess deaths among HIV positive adults by diagnosis, care and treatment history in African population based cohorts 2007-2011.
    20th International AIDS Conference (2014). (Melbourne)
    Authors: Slaymaker E, Hosegood V,

    A comparative analysis of national HIV policies in six African countries with generalised epidemics: Influences on access to testing, access to treatment and retention in care.
    20th International AIDS Conference (2014). (Melbourne)
    Authors: Zaba B, Hosegood V,